Relay-Version: version B 2.10 5/3/83; site utzoo.UUCP Path: utzoo!utgpu!water!watmath!uunet!ig!daemon From: daemon@ig.UUCP Newsgroups: bionet.molbio.news Subject: CSLG|COMMENTARY: From Ellis Golub Message-ID: <4259@ig.ig.com> Date: Tue, 1-Dec-87 14:37:43 EST Article-I.D.: ig.4259 Posted: Tue Dec 1 14:37:43 1987 Date-Received: Sat, 5-Dec-87 13:16:42 EST Sender: daemon@presto.ig.com Lines: 21 From: Sunil MaulikComputer Applications in the Sequencing of Large Genomes It is trivial to assert that computer programs of the type currently available on BIONET and numerous other general purpose molecular biology software packages will play a key role in the massive sequencing projects envisioned for the near future. The difficult tasks of accumulating the large number of fragment sequences required and of assembling these fragments into coherent sequences, and to keep track of the immense volume of sequence data are natural applications for computers. However, management of cloning and sequencing is only the smallest and most mechanical aspect of the application of computers to the large genome project. It would be more accurate to say that there would be no point to accumulating large amounts of sequence data if electronic data processing methods were not available to make the data useful to the scientific community. Further, in anticipation of the glut of data to come, it is likely that currently available software and hardware will not be adequate to prevent us from drowning in our own data. -------