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Subject: CSLG|COMMENTARY: From Ellis Golub
Message-ID: <4259@ig.ig.com>
Date: Tue, 1-Dec-87 14:37:43 EST
Article-I.D.: ig.4259
Posted: Tue Dec  1 14:37:43 1987
Date-Received: Sat, 5-Dec-87 13:16:42 EST
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From: Sunil Maulik 

         Computer Applications in the Sequencing of Large Genomes

    It is trivial to assert that computer programs of the type currently 
available on BIONET and numerous other general purpose molecular biology 
software packages will play a key role in the massive sequencing projects 
envisioned for the near future. The difficult tasks of accumulating the 
large number of fragment sequences required and of assembling these 
fragments into coherent sequences, and to keep track of the immense volume 
of sequence data are natural applications for computers. However, 
management of cloning and sequencing is only the smallest and most 
mechanical aspect of the application of computers to the large genome 
project. It would be more accurate to say that there would be no point to 
accumulating large amounts of sequence data if electronic data processing 
methods were not available to make the data useful to the scientific 
community. Further, in anticipation of the glut of data to come, it is 
likely that currently available software and hardware will not be adequate 
to prevent us from drowning in our own data.

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