Path: utzoo!utgpu!water!watmath!uunet!ig!bionet-20.bio.net!EBEALE From: EBEALE@BIONET-20.BIO.NET (Elmus Beale) Newsgroups: bionet.molbio.methds-reagnts Subject: Analysis of RNA-RNA hybrids Message-ID: <12410127855.41.EBEALE@BIONET-20.ARPA> Date: 28 Jun 88 21:08:21 GMT Sender: daemon@presto.ig.com Lines: 8 Does RNase A digest single-stranded RNA only? The general consensus is that it does but I can't find any references that describe its activities on single vs. double stranded RNA. I am trying to use it to analyze RNA-RNA hybrids but everything is digested (and becomes TCA soluble). Does anyone have any experience with this problem and could offer suggestions? Elmus Beale -------