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From: ix21@sdccs6.UUCP
Newsgroups: net.med
Subject: Re: Folic Acid
Message-ID: <1237@sdccs6.UUCP>
Date: Thu, 8-Mar-84 01:22:36 EST
Article-I.D.: sdccs6.1237
Posted: Thu Mar  8 01:22:36 1984
Date-Received: Fri, 9-Mar-84 01:55:18 EST
References: <210@metheus.UUCP>
Organization: U.C. San Diego, Computer Center
Lines: 18

Metheus!howard asks if there is any justification to FDA's
recommendation to limit the amount of folic acid in oral tablets to
1 mg.  The side effects to folic acid toxicity are not limited to
masking the diagnosis of pernecious anemia.  Other side-effects
are attributed to high levels of folic acid including the
possibility of seizures. {Reynolds, E. H. Neurological aspects of
folate and vitamin B12 metabolism. Clinical Haematology. 1976, 5,
661-696.

In addition there is additional evidence that excess vitamins
administered to pregnant females may result in the child having an
increase need for vitamins.

-- 
David Whiteman sdcsvax!sdccs6!whiteman
UCSD Medical School, La Jolla CA
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