Relay-Version: version B 2.10 5/3/83; site utzoo.UUCP Posting-Version: version B 2.10.1 6/24/83; site sdccs6.UUCP Path: utzoo!watmath!clyde!floyd!harpo!decvax!ittvax!dcdwest!sdcsvax!sdccs6!ix21 From: ix21@sdccs6.UUCP Newsgroups: net.med Subject: Re: Folic Acid Message-ID: <1237@sdccs6.UUCP> Date: Thu, 8-Mar-84 01:22:36 EST Article-I.D.: sdccs6.1237 Posted: Thu Mar 8 01:22:36 1984 Date-Received: Fri, 9-Mar-84 01:55:18 EST References: <210@metheus.UUCP> Organization: U.C. San Diego, Computer Center Lines: 18 Metheus!howard asks if there is any justification to FDA's recommendation to limit the amount of folic acid in oral tablets to 1 mg. The side effects to folic acid toxicity are not limited to masking the diagnosis of pernecious anemia. Other side-effects are attributed to high levels of folic acid including the possibility of seizures. {Reynolds, E. H. Neurological aspects of folate and vitamin B12 metabolism. Clinical Haematology. 1976, 5, 661-696. In addition there is additional evidence that excess vitamins administered to pregnant females may result in the child having an increase need for vitamins. -- David Whiteman sdcsvax!sdccs6!whiteman UCSD Medical School, La Jolla CA {insert boring .signature file here}